Use of Tranexamic Acid with microneedling for the treatment of Melasma – case report

Vol. 4 – Number 16 – 2023 Case report Page 50-62 Use of Tranexamic Acid with microneedling for the treatment of Melasma – case report Sylvia Tavares Barros1 Pedro Carvalho Feitosa2 Kelly Martins3 Alexandre Miyahira4 ABSTRACT Aesthetics and beauty are in the spotlight, especially when it comes to aesthetic dysfunctions and their impact on people’s lives. The skin undergoes a variety of changes, be it expression lines, wrinkles, scars or spots. Specifically, the focus of this study is Melasma, which is characterized by brown spots that mainly affect the face of women of childbearing age. It is a skin pigment disorder that is often treated as a simple nuisance, but which can affect self-esteem, influencing social relationships and causing strong emotional stress. Although there are therapeutic alternatives to improve the appearance of the skin, more abrasive treatments that induce collagen have a slower recovery and greater risks. Microneedling has emerged as a safe and effective alternative because, through skin perforations and the inflammatory process, it allows the release of growth factors, stimulating collagen production. And, associated with tranexamic acid (ATX), which is a synthetic derivative of lysine, it inhibits melanin production, with a lightening effect on existing spots and prevents pigmentation induced by ultraviolet rays, preventing other spots from appearing. The purpose of this study was to observe the effects of using tranexamic acid to treat Melasma using a methodology based on the literature. We observed mild results, but with the potential for improvement if using longer treatment with at least 3 months of Home Care. Descriptors: Melasma, microneedling, tranexamic acid. 1 Graduate in Dentistry – UNIP. 2 Specialist Mesre and Dr. in Implantology, Specialist in Surgery and Traumatology-Oral and Maxillofacial, Specialist in Orofacial Harmonization. 3 Specialist in Facial Harmonization and Specialist in Orthodontics. 4 Master’s student in Implantology – UNISA, Specialist in Orofacial Harmonization. DOI: 10.24077/2023;416031485799