Use of platelet rich-plasma and injectable platelet rich-fibrin as facial rejuvenation therapies

Vol. 2 – Number 5 – 2020 Literature review Page 92-97 Use of platelet rich-plasma and injectable platelet rich-fibrin as facial rejuvenation therapies Kely Pereira Borges¹ Sidmarcio Ziroldo² ABSTRACT The autologous concentrates of platelets and of growth factors have been used as a therapeutic option for facial rejuvenation, as they provide a biostimulation in the production of collagen. Platelet Rich-Plasma (PRP) and Injectable Platelet Rich-Fibrin (i-PRF) are safe options, without allergic reactions, and are autologous materials with reduced production costs, and with different protocols and presentations. The aim of this study was to highlight the benefits and specificities of the application of PRP and i-PRF in the treatment of interfacial rejuvenation, in the current clinical activities of aesthetic treatment in the Dentistry field based on clinical evidence. It was based on a systematic search of qualitative nature in databases, evaluating electronic scientific articles published between the years 2013 to 2020. Searches in English and Portuguese were included, with the terms [“platelet rich plasma” OR “Platelet Rich Fibrin Injectable “] AND [“Facial Rejuvenation” OR “rejuvenation”], investigating clinical applications in the studies. The results achieved after therapy with the autologous concentrates PRP and i-PRF report the improvement in the skin appearance and promote the reduction of wrinkles. More detailed studies are needed in order to clarify their quantification and qualification, and the standardization of the methods to obtain these concentrates, in order to expand their use in the aesthetic practice of facial rejuvenation. Descriptors: Platelet rich-plasma, injectable platelet rich-fibrin, facial rejuvenation. ¹ Dentistry – UFU, Orthodontist. ² Master in Orthodontics, Esp. in CTBMF, Esp. in Orofacial Harmonization. DOI: 10.24077/2020;25-9297